| Identification | Back Directory | [Name]
CCR1 inhibitor 19e | [CAS]
1220026-26-5 | [Synonyms]
CCR1 antagonist 9
CCR1 inhibitor 19e
CCR1 antagonist 9,CCR-1 antagonist 9
1H-Pyrazolo[3,4-c]pyridine-4-carboxamide, 1-(4-fluorophenyl)-N-[[2-(methylsulfonyl)-4-pyridinyl]methyl]- | [Molecular Formula]
C20H16FN5O3S | [MDL Number]
MFCD32671356 | [MOL File]
1220026-26-5.mol | [Molecular Weight]
425.44 |
| Chemical Properties | Back Directory | [Boiling point ]
723.7±60.0 °C(Predicted) | [density ]
1.46±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
11.11±0.46(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
CCR1 antagonist 9 is a potent and selective CCR1 antagonist with an IC50?of?6.8 nM in calcium flux assay[1]. | [IC 50]
CCR1: 6.8 nM (IC50, in calcium flux assay) | [References]
[1] Harcken C, et al. Identification of novel azaindazole CCR1 antagonist clinical candidates. Bioorg Med Chem Lett. 2019 Feb 1;29(3):441-448. DOI:10.1016/j.bmcl.2018.12.024 |
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BOC Sciences
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1-631-485-4226; 16314854226 |
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https://www.bocsci.com |
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cjbscvictory
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13348960310 |
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https://www.weikeqi-biotech.com/ |
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