ChemicalBook--->CAS DataBase List--->12211-28-8

12211-28-8

12211-28-8 Structure

12211-28-8 Structure
IdentificationBack Directory
[Name]

Proteinase, Bacillus subtilis, sutilain
[CAS]

12211-28-8
[EINECS(EC#)]

235-390-3
Chemical PropertiesBack Directory
[EPA Substance Registry System]

Proteinase, Bacillus subtilis, sutilains (12211-28-8)
Safety DataBack Directory
[Symbol(GHS) ]


GHS08,GHS07
[Signal word ]

Danger
[Hazard statements ]

H319-H334
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P261-P285-P304+P341-P342+P311-P501
Hazard InformationBack Directory
[Uses]

Enzyme (proteolytic).
[Brand name]

Travase (Abbott).
[General Description]

Sutilains (Travase) is a proteolyticenzyme obtained from cultures of Bacillus subtilis and usedto dissolve necrotic tissue occurring in second- and thirddegreeburns as well as bed sores and ulcerated wounds.
Many substances are contraindicated during the topicaluse of sutilains. These include detergents and anti-infectivesthat denature the enzyme preparation. The antibioticspenicillin, streptomycin, and neomycin do not inactivatesutilains. Mafenide acetate is also compatible with theenzyme.
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