| Identification | Back Directory | [Name]
Benzamide, N-(3S)-1-azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxy- | [CAS]
1221570-55-3 | [Synonyms]
Benzamide, N-(3S)-1-azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxy- | [Molecular Formula]
C16H22N2O3 | [MOL File]
1221570-55-3.mol | [Molecular Weight]
290.36 |
| Chemical Properties | Back Directory | [Boiling point ]
439.0±45.0 °C(Predicted) | [density ]
1.20±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 2mg/mL, clear | [form ]
powder | [pka]
13.88±0.20(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Biological Activity]
PSEM89S is a pharmacologically selective effector molecule (PSEM) th at acts as a selective agonist in vitro and in vivo for chimeric pharmacologically selective actuator modules (PSAMs) composed of nAChR α7 ligand-binding domain (LBD) with L141F mutation fused to the ion pore domain (IPD) of a ligand-gated ion channel (LGIC)including glycine receptor (PSAML141F-GlyR & PSAML141F/Y115F-GlyR). 5-HT3 (PSAML141F-5-HT3 & PSAML141F/Y115F-5-HT3) and high-conductance 5-HT3 (PSAML141F-5-HT3 HC & PSAML141F/Y115F-5-HT3 HC). |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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