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Chemical PropertiesBack Directory
[density ]

1.55±0.1 g/cm3(Predicted)
[pka]

8.41±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

(R)-Larotrectinib is a potent TRK inhibitor with an IC50 value of 28.5 nM for TrkA. (R)-Larotrectinib can be used for researching cancer, inflammatory and certain infectious diseases[1]
[IC 50]

TrkA: 28.5 nM (IC50)
[References]

[1] Julia Haas, et al. SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS. WO2010048314A1 (compound 93)
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