122479-08-7

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122479-08-7 Structure

Identification	Back Directory
[Name] 2-(4-AMINOPHENYL)-3-METHOXY-6-(3-METHOXYPHENYL)-METHYLIMIDAZO[1,2-B]PYRIDAZINE
[CAS] 122479-08-7
[Synonyms] GBLD 345 2-(4-AMINOPHENYL)-3-METHOXY-6-(3-METHOXYPHENYL)-METHYLIMIDAZO[1,2-B]PYRIDAZINE Imidazo[1,2-b]pyridazin-6-amine, 2-(4-aminophenyl)-3-methoxy-N-[(3-methoxyphenyl)methyl]-
[Molecular Formula] C21H21N5O2
[MDL Number] MFCD00673920
[MOL File] 122479-08-7.mol
[Molecular Weight] 375.42

Chemical Properties	Back Directory
[density ] 1.29±0.1 g/cm3(Predicted)
[storage temp. ] Store at RT
[solubility ] Soluble in ethanol or DMSO
[pka] 4.37±0.30(Predicted)

Hazard Information	Back Directory
[Uses] GBLD345, a nonbenzodiazepine anxiolytic agent, is a non- selective, potent GABAA receptor positive allosteric modulator (PAM)[1].
[Biological Activity] A high affinity benzodiazepine agonist (IC 50 against diazepam = 1 nM).
[storage] Store at RT
[References] [1] Mohd Imran, Mohammad Asif Study of Various Pyridazine and Phthalazine Drugs with Diverse Therapeutical and Agrochemical Activities. Russ J Bioorg Chem 46, 745-767 (2020).

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