| Identification | Back Directory | [Name]
PROTRIPTYLINE HYDROCHLORIDE | [CAS]
1225-55-4 | [Synonyms]
mk-240
maximed
concordin
normethylex4442
PROTRIPTYLINE HCL
triptilhydrochloride
Protriptylin hydrochloride
PROTRIPTYLINE HYDROCHLORIDE
Protriptyline HCl, 1.0 mg/mL
Protriptyline Hydrochloride (200 mg)
Protriptyline hydrochloride solution
d)cyclohepten-5-propylamine,n-methyl-5h-dibenzo(hydrochloride
n-methyl-5h-dibenzo(a,d)cycloheptene-5-propylaminehydrochloride
5-(3-methylaminopropyl)-5h-dibenzo(a,d)cycloheptenehydrochloride
N-Methyl-5H-dibenzo[a,d]cycloheptene-5-propanamine hydrochloride
5H-Dibenzo[A,D]cyclohepten-5-propylamine, N-methyl-, hydrochloride
5H-Dibenzo[A,D]cycloheptene-5-propanamine, N-methyl-, hydrochloride
5H-Dibenzo[A,D]cycloheptene-5-propylamine, N-methyl-, hydrochloride
3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-Methylpropan-1-aMine hydrochloride | [EINECS(EC#)]
214-956-3 | [Molecular Formula]
C19H22ClN | [MDL Number]
MFCD00072057 | [MOL File]
1225-55-4.mol | [Molecular Weight]
299.84 |
| Chemical Properties | Back Directory | [Melting point ]
169-171° | [Fp ]
9℃ | [storage temp. ]
2-8°C | [solubility ]
H2O: soluble50mg/mL | [form ]
powder | [pka]
8.2(at 25℃) | [color ]
white to off-white | [Water Solubility ]
H2O: 50mg/mL | [Stability:]
Hygroscopic | [InChI]
InChI=1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-10,12-13,19-20H,6,11,14H2,1H3;1H | [InChIKey]
OGQDIIKRQRZXJH-UHFFFAOYSA-N | [SMILES]
C1(CCCNC)C2C=CC=CC=2C=CC2C=CC=CC1=2.Cl |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,T,F | [Risk Statements ]
20/21/22-36/37/38-39/23/24/25-23/24/25-11 | [Safety Statements ]
26-36-45-36/37-16-7 | [RIDADR ]
3249 | [WGK Germany ]
3 | [RTECS ]
HP1400000 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [HS Code ]
2921490002 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 | [Toxicity]
dog,LDLo,oral,400mg/kg (400mg/kg),"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 88, 1972. |
| Hazard Information | Back Directory | [Uses]
Monoamine reuptake inhibitor; tricyclic antidepressant. | [Brand name]
Vivactil (Odyssey). | [General Description]
Protriptyline hydrochloride, N-methyl-5H-dibenzo[a,d]-cycloheptene-5-propylamine hydrochloride, 5-(3-methylaminopropyl)-5H-dibenzo[a,d]cycloheptene hydrochloride(Vivactil), like the other compounds under consideration, isan effective antidepressant. The basis for its chemical namingcan be seen by consulting the naming and the structureof imipramine. Protriptyline is a structural isomer of nortriptyline.Inactivation can be expected to involve the relativelylocalized double bond. Because it is a monomethylcompound, its sedative potential is low. | [Biochem/physiol Actions]
Norepinephrine uptake blocker. |
|
| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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