| Identification | Back Directory | [Name]
2-Dodecanol, 1,1′-[[2-[4-[2-[[2-[bis[(2S)-2-hydroxydodecyl]amino]ethyl][(2S)-2-hydroxydodecyl]amino]ethyl]-1-piperazinyl]ethyl]imino]bis-, (2S,2′S)- | [CAS]
1226552-44-8 | [Synonyms]
2-Dodecanol, 1,1′-[[2-[4-[2-[[2-[bis[(2S)-2-hydroxydodecyl]amino]ethyl][(2S)-2-hydroxydodecyl]amino]ethyl]-1-piperazinyl]ethyl]imino]bis-, (2S,2′S)- | [Molecular Formula]
C70H145N5O5 | [MOL File]
1226552-44-8.mol | [Molecular Weight]
1136.93 |
| Chemical Properties | Back Directory | [Boiling point ]
1017.6±65.0 °C(predicted) | [density ]
0.948±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [solubility ]
Ethanol: Soluble | [pka]
14.45±0.20(predicted) |
| Hazard Information | Back Directory | [Uses]
(S)-C12-200 is the (S)-isomer of C12-200 (HY-145405), an ionizable cationic lipid and helper lipid. (S)-C12-200 can be utilized in the formation of lipid nanoparticles and mRNA delivery[1]. | [References]
[1] Da Silva Sanchez AJ, et al. Substituting racemic ionizable lipids with stereopure ionizable lipids can increase mRNA delivery. J Control Release. 2023 Jan;353:270-277. DOI:10.1016/j.jconrel.2022.11.037 |
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