| Identification | Back Directory | [Name]
CCX-777 | [CAS]
1226686-36-7 | [Synonyms]
CCX-777
1H-1,4-Diazepine-1-propanamide, hexahydro-4-(7-methoxy-8-quinolinyl)-β-[2-(4-morpholinyl)-4-thiazolyl]-N-[2-(1-pyrrolidinyl)ethyl]- | [Molecular Formula]
C31H43N7O3S | [MOL File]
1226686-36-7.mol | [Molecular Weight]
593.79 |
| Chemical Properties | Back Directory | [density ]
1.250±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, away from moisture and light | [form ]
Solid | [pka]
15.37±0.46(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
CCX-777 is a partial agonist of β-arrestin-2 recruitment to ACKR3 (atypical chemokine receptor 3)[1]. | [References]
[1] Gustavsson M, et al. Structural basis of ligand interaction with atypical chemokine receptor 3. Nat Commun. 2017 Jan 18;8:14135. DOI:10.1038/ncomms14135 |
|
|