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1228105-52-9

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1228105-52-9 Structure

1228105-52-9 Structure
IdentificationBack Directory
[Name]

DM4-SMCC
[CAS]

1228105-52-9
[Synonyms]

DM4-SMCC
SMCC-DM4
Maytansine, N2'-deacetyl-N2'-[4-[[1-[[4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl]methyl]-2,5-dioxo-3-pyrrolidinyl]thio]-4-methyl-1-oxopentyl]-
[Molecular Formula]

C54H72ClN5O16S
[MDL Number]

MFCD30378972
[MOL File]

1228105-52-9.mol
[Molecular Weight]

1114.7
Chemical PropertiesBack Directory
[density ]

1.38±0.1 g/cm3(Predicted)
[pka]

9.82±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

SMCC-DM4 is a mertansine drug with a reactive linker SMCC to make antibody drug conjugate. DM1 (mertansine), a thiol-containing maytansinoid, is a potent microtubule-disrupting agent.
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