| Identification | Back Directory | [Name]
Fenbendazole-d3 | [CAS]
1228182-47-5 | [Synonyms]
Fenbendazole-d3
[2H3]-Fenbendazole
Fenbendazole-d3
Fenbendazole-d3 (methyl-d3)
N-[6-(Phenylthio)-1H-benziMidazol-2-yl]carbaMic Acid Methyl-d3 Ester | [Molecular Formula]
C15H12N3O2S | [MDL Number]
MFCD16652570 | [MOL File]
1228182-47-5.mol | [Molecular Weight]
298.34 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: slightly soluble,Methanol: slightly soluble | [form ]
neat | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Description]
Fenbendazole-d3 is intended for use as an internal standard for the quantification of fenbendazole (Item No. 19687) by GC- or LC-MS. Fenbendazole is a benzimidazole anthelmintic.1 It is active against Giardia in vitro (IC50 = 0.3 μM). Fenbendazole (20 mg/kg) prevents infiltration of parasites into the brain in a rabbit model of E. cuniculi infection.2 It also activates HIF-1α and prevents oxidative stress-induced death in primary neurons in vitro.3 | [Uses]
Labelled Fenbendazole (F246750). An anthelmintic (Nematodes). | [storage]
Store at -20°C | [References]
[1] U M MORGAN R C T J A Reynoldson. Activities of several benzimidazoles and tubulin inhibitors against Giardia spp. in vitro.[J]. Antimicrobial Agents and Chemotherapy, 1993, 37 2: 328-331. DOI: 10.1128/aac.37.2.328
[2] C. SUTER. Prevention and treatment of Encephalitozoon cuniculi infection in rabbits with fenbendazole[J]. Veterinary Record, 2001, 16 1: 478-480. DOI: 10.1136/vr.148.15.478
[3] HOSSEIN ALEYASIN. Antihelminthic benzimidazoles are novel HIF activators that prevent oxidative neuronal death via binding to tubulin.[J]. Antioxidants & redox signaling, 2015, 22 2: 121-134. DOI: 10.1089/ars.2013.5595 |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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