| Identification | Back Directory | [Name]
Pydiflumetofen | [CAS]
1228284-64-7 | [Synonyms]
Adepidyn
Pydiflumetofen
1H-Pyrazole-4-carboxamide, 3-(difluoromethyl)-N-methoxy-1-methyl-N-[1-methyl-2-(2,4,6-trichlorophenyl)ethyl]- | [Molecular Formula]
C16H16Cl3F2N3O2 | [MOL File]
1228284-64-7.mol | [Molecular Weight]
426.67 |
| Chemical Properties | Back Directory | [Melting point ]
>96°C (dec.) | [Boiling point ]
557.9±50.0 °C(Predicted) | [density ]
1.44±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
-2.27±0.10(Predicted) | [color ]
Off-White | [Henry's Law Constant]
6.6×103 mol/(m3Pa) at 25℃, Ebert et al. (2023) | [Stability:]
Hygroscopic | [EPA Substance Registry System]
Pydiflumetofen (1228284-64-7) |
| Hazard Information | Back Directory | [Description]
Pydiflumetofen is a broad-spectrum fungicide. It has a low aqueous solubility and a low volatility. It may be persistent in both soil and water systems depending upon local conditions. It is not highly toxic to mammals but it may be a liver and/or thyroid toxicant. It is highly toxic to most aquatic species. | [Uses]
Pydiflumetofen is used in the preparation of carboxamides as plant growth enhancers in crops. | [Definition]
ChEBI: 3-(difluoromethyl)-N-methoxy-1-methyl-N-[1-(2,4,6-trichlorophenyl)propan-2-yl]pyrazole-4-carboxamide is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of 3-(difluoromethyl)-1-methylpyrazole-4-carboxylic acid with the amino group of N-methoxy-1-(2,4,6-trichlorophenyl)propan-2-amine. It is a trichlorobenzene, a monocarboxylic acid amide, an aromatic amide, a member of pyrazoles and an organofluorine compound. | [Mechanism of action]
Succinate Dehydrogenase Inhibitor (SDHI) | [Synthesis]
The preparation method of pydiflumetofen comprises the following steps: (1) performing a reaction on p-chloroaniline and isopropenyl acetate to obtain 4'-chloropropiophenone; (2) performing benzene ring chlorination to obtain 2',4',6'-trichloropropiophenone; (3) performinga carbonyl reduction reaction to obtain 1-(2',4',6'-trichlorophenyl)-2-propanol; (4) performing hydroxyl halogenation to obtain 1-(2',4',6-trichlorophenyl)-2-chloropropane; (5) performing amination on 1-(2,4,6-trichlorophenyl)-2-chloropropane and O-methylhydroxylamine to obtain O-methyl N-[1-methyl-2-(2,4,6-trichlorophenyl)-ethyl]-hydroxylamine; (6) performing a substitution reaction on the product obtained in step (5) and 3-difluoromethyl-1-methyl-1H-pyrazole-4-carbonyl chloride under the action of an acid binding agent to obtain pydiflumetofen.
| [Pesticide Type]
Fungicide; Plant Growth Regulator |
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