| Identification | Back Directory | [Name]
1H-Imidazo[4,5-c]quinoline-1-ethanol, 4-amino-2-butyl-α,α-dimethyl- | [CAS]
1229024-78-5 | [Synonyms]
TLR7 agonist 3
1H-Imidazo[4,5-c]quinoline-1-ethanol, 4-amino-2-butyl-α,α-dimethyl-
1-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol | [Molecular Formula]
C18H24N4O | [MOL File]
1229024-78-5.mol | [Molecular Weight]
312.42 |
| Chemical Properties | Back Directory | [Boiling point ]
552.9±40.0 °C(Predicted) | [density ]
1.23±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
14.66±0.29(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
TLR7-Agonist-54 is a highly potent TLR7 agonist. | [Uses]
TLR7 agonist 3 (Compound 2) is a potent agonist of toll-like receptor 7 (TLR7). TLR7 has an important role in immune activation processes and represents an emerging agent discovery target for the development of immunomodulators[1]. | [IC 50]
TLR7 | [References]
[1] Urban ?vajger, et al. New antagonists of toll-like receptor 7 discovered through 3D ligand-based virtual screening. Medicinal Chemistry Research. 2015. 24: 362-371. |
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Biorbyt Ltd.
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+44 (0)1223 859 353 |
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http://www.biorbyt.com |
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