| Identification | Back Directory | [Name]
LY2828360 | [CAS]
1231220-79-3 | [Synonyms]
CS-2878
LY2828360
8-(2-chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-(tetrahydro-2H-pyran-4-yl)-9H-purine
9H-Purine, 8-(2-chlorophenyl)-2-methyl-6-(4-methyl-1-piperazinyl)-9-(tetrahydro-2H-pyran-4-yl)- | [Molecular Formula]
C22H27ClN6O | [MDL Number]
MFCD28010855 | [MOL File]
1231220-79-3.mol | [Molecular Weight]
426.94 |
| Chemical Properties | Back Directory | [Boiling point ]
541.8±60.0 °C(Predicted) | [density ]
1.40±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Chloroform: 30 mg/ml | [form ]
A crystalline solid | [pka]
7.15±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Biological Activity]
LY2828360 is a potent and selective slowly acting G protein-biased CB2 cannabinoid agonist th at inhibits cAMP accumulation and activates ERK1/2 signaling while failing to recruit arrestin. LY2828360 suppress chemotherapy-induced neuropathic pain created by paclitaxel without producing tolerance in mice. |
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| Company Name: |
Cckinase, Inc.
|
| Tel: |
+1 (732)236-3202 |
| Website: |
www.cckinase.com |
|