| Identification | Back Directory | [Name]
1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine | [CAS]
123284-81-1 | [Synonyms]
1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine | [Molecular Formula]
C49H74NO8P | [MOL File]
123284-81-1.mol | [Molecular Weight]
836.09 |
| Chemical Properties | Back Directory | [Boiling point ]
824.5±75.0 °C(Predicted) | [density ]
1.037±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
liquid | [pka]
1.17±0.50(Predicted) | [InChIKey]
RBDNSJMXMWTPCS-NYUVKXDYSA-N | [SMILES]
[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O)COC(CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O |
| Hazard Information | Back Directory | [Uses]
22:6 PE has been used as a standard for the optimization of liquid chromatography-mass spectrometry (LC/MS) conditions and to detect the serum antiphosphatidylethanolamine (aPE) antibodies from patients using enzyme linked immunosorbent assay (ELISA). It is suitable for use in testing the effect of increasing acyl chain unsaturation on phase separation from the lipid raft molecules spingomyelin (SM) and cholesterol (CHOL). | [Definition]
ChEBI: 1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine is a 1,2-diacyl-sn-glycero-3-phosphoethanolamine in which both the acyl groups specified is (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl. It has a role as a mouse metabolite. It is functionally related to an all-cis-docosa-4,7,10,13,16,19-hexaenoic acid. | [General Description]
22:6 PE is a polyunsaturated homoacid. Phosphatidylethanolamine (PE) is a membrane phospholipid. The types of PE depends on the combination of free fatty acids on the α and β position. 22:6 PE denotes the length of the carbon chain:degree of unsaturation in the PE. | [Biochem/physiol Actions]
Phosphatidylethanolamine (PE) plays a key role in membrane fusion, cell cycle, autophagy, apoptosis, and cognitive function. |
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Sigma-Aldrich
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https://www.sigmaaldrich.cn |
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