| Hazard Information | Back Directory | [Description]
TASP0412098 is a novel potent, selective, and orally active CRTH2 antagonist. | [Uses]
TASP0412098 is an orally available, potent and selective CRTH2/DP2 antagonist with high binding affinity (IC50 2.1 nM) and functional activity (IC50 12 nM). TASP0412098 has the potential to suppress asthma in mouse and guinea pig bronchial asthma models[1]. | [References]
[1] Isoquinoline Derivatives as Potent, Selective, and Orally Active CRTH2 Antagonists |
|
|