| Identification | Back Directory | [Name]
Lalistat 2 | [CAS]
1234569-09-5 | [Synonyms]
Lalistat 2
Lalistat 2 >=98% (HPLC)
4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl piperidine-1-carboxylate
lysosomal acid lipase deficiency,dried blood spot,Lalistat2,Lalistat-2,Inhibitor,cholesteryl ester storage disease,Lalistat 2,inhibit | [Molecular Formula]
C13H20N4O2S | [MDL Number]
MFCD31544494 | [MOL File]
1234569-09-5.mol | [Molecular Weight]
296.39 |
| Chemical Properties | Back Directory | [Boiling point ]
438.5±45.0 °C(Predicted) | [density ]
1.295±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS(pH 7.2) (1:5): 0.16 mg/ml | [form ]
A crystalline solid | [pka]
5.53±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Lalistat 2 is used in the synthetic preparation of thiadiazole carbamates as inhibitors of lysosomal acid lipase and potential Niemann-Pick type C disease therapeutics. | [Biological Activity]
Lalistat-2 is a potent and specific competitive inhibitor of the lysosomal acid lipase (LAL/Lipa). Lalistat-2 affects lipid droplets morphology and localization. | [storage]
Store at +4°C |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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