| Identification | Back Directory | [Name]
3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile | [CAS]
123548-56-1 | [Synonyms]
TYB 2285
Acreozast
VNVBCWREJHKWSG-UHFFFAOYSA-N
3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile
Acetamide, N,N'-(2-chloro-5-cyano-1,3-phenylene)bis[2-(acetyloxy)- | [Molecular Formula]
C15H14ClN3O6 | [MDL Number]
MFCD00882556 | [MOL File]
123548-56-1.mol | [Molecular Weight]
367.74 |
| Chemical Properties | Back Directory | [Melting point ]
193-195 °C(Solv: ethanol (64-17-5)) | [Boiling point ]
588.3±50.0 °C(Predicted) | [density ]
1.43±0.1 g/cm3(Predicted) | [pka]
10.67±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
Acreozast (TYB-2285) is a histamine release inhibitor. Acreozast inhibits the histamine release primed with IL-3. Acreozast might regulate allergic inflammation in vivo by the suppression of mediator release primed with IL-3[1]. | [References]
[1] Watanabe A, et al. Effect of TYB-2285 on antigen-induced histamine release from mouse bone marrow-derived persisting cells (P-cells) primed with interleukin-3-containing conditioned medium (IL3-CM). Gen Pharmacol. 1993 Sep;24(5):1207-11. DOI:10.1016/0306-3623(93)90370-d |
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