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1236525-13-5

1236525-13-5 Structure

1236525-13-5 Structure
IdentificationBack Directory
[Name]

(S)-Methyl 3-aminopentanoate hydrochloride
[CAS]

1236525-13-5
[Synonyms]

(S)-methyl 3-aminopentanoate HCl
(S)-Methyl 3-aminopentanoate hydrochloride
(S)-Methyl 3-aminopentanoate hydrochloride ee
[Molecular Formula]

C6H14ClNO2
[MDL Number]

MFCD16877220
[MOL File]

1236525-13-5.mol
[Molecular Weight]

167.63
Chemical PropertiesBack Directory
[storage temp. ]

Sealed in dry,Room Temperature
Hazard InformationBack Directory
[Synthesis]

Methanol

67-56-1

(S)-3-Aminopentanoic acid

14389-77-6

(S)-Methyl 3-aminopentanoate hydrochloride

1236525-13-5

Example 2: Synthesis of methyl (S)-3-aminopentanoate hydrochloride: 500 mg of (S)-3-aminopentanoic acid was added to a 10 mL methanol solution containing 0.6 mL of acetyl chloride at room temperature. The reaction mixture was stirred at 60 °C for 18 hours. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently concentrated under vacuum. The resulting light tan oil was (S)-3-aminopentanoic acid methyl ester hydrochloride, which could be used directly in the subsequent reaction steps without further purification. Yield: 714 mg, yield: 99%.

[References]

[1] Patent: WO2010/88195, 2010, A1. Location in patent: Page/Page column 26
[2] Patent: WO2017/21729, 2017, A1. Location in patent: Page/Page column 40
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