| Identification | Back Directory | [Name]
((3R,4R)-4-aMinotetrahydro-2H-pyran-3-yl)carbaMate | [CAS]
1240390-36-6 | [Synonyms]
(3R,4R)-N3-Boc-tetrahydro-2H-pyran-3,4-diamine
((3R,4R)-4-aMinotetrahydro-2H-pyran-3-yl)carbaMate
tert-butyl N-[(3R,4R)-4-aminotetrahydropyran-3-yl]carbamate
tert-butyl ((3R,4R)-4-aMinotetrahydro-2H-pyran-3-yl)carbaMate
Carbamic acid, N-[(3R,4R)-4-aminotetrahydro-2H-pyran-3-yl]-, 1,1-dimethylethyl ester | [EINECS(EC#)]
604-604-1 | [Molecular Formula]
C10H20N2O3 | [MDL Number]
MFCD19105154 | [MOL File]
1240390-36-6.mol | [Molecular Weight]
216.28 |
| Hazard Information | Back Directory | [Synthesis]
Step 8: Tert-butyl (3R,4R)-4-azidotetrahydro-2H-pyran-3-ylcarbamate (700 mg, 2.89 mmol) was dissolved in ethanol (10 mL) and palladium/carbon hydroxide catalyst was added. The reaction was carried out under hydrogen (1 atm) atmosphere for 6 hours. After completion of the reaction, the palladium/carbon hydroxide was removed by filtration and the filtrate was concentrated to afford tert-butyl (3R,4R)-4-aminotetrahydro-2H-pyran-3-ylcarbamate (610 mg). | [References]
[1] Patent: WO2010/97248, 2010, A1. Location in patent: Page/Page column 38-39
[2] Patent: WO2013/78468, 2013, A1. Location in patent: Paragraph 0747; 0755
[3] Patent: US2017/15655, 2017, A1. Location in patent: Paragraph 1474-1475 |
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Cool Pharm, Ltd
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021-58581007 18019463053 |
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www.coolpharm.com.cn |
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