| Identification | Back Directory | [Name]
D-allo-Heptitol, 3,6-anhydro-1,2-dideoxy-1-(5-phenyl-2H-tetrazol-2-yl)-, 7-[N-[(2S,3S)-2-amino-3-methyl-1-oxopentyl]sulfamate] | [CAS]
1241942-59-5 | [Synonyms]
CB 168
D-allo-Heptitol, 3,6-anhydro-1,2-dideoxy-1-(5-phenyl-2H-tetrazol-2-yl)-, 7-[N-[(2S,3S)-2-amino-3-methyl-1-oxopentyl]sulfamate] | [Molecular Formula]
C20H30N6O7S | [MOL File]
1241942-59-5.mol | [Molecular Weight]
498.56 |
| Hazard Information | Back Directory | [Uses]
CB 168 is a potent and selective aminoacyl-sulfamoyl aryltetrazole inhibitor targeting isoleucyl-tRNA synthetase (IleRS)[1]. | [References]
[1] De Ruysscher D, et al. Phenyltriazole-functionalized sulfamate inhibitors targeting tyrosyl- or isoleucyl-tRNA synthetase. Bioorg Med Chem. 2020 Aug 1;28(15):115580. DOI:10.1016/j.bmc.2020.115580 |
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