| Identification | Back Directory | [Name]
(R)-3-Methyl-1-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)butan-1-aMine hydrochloride | [CAS]
1243174-57-3 | [Synonyms]
(R)-(1-AMINO-3-METHYLBUTYL)BORONIC ACID HCL PINACOL ESTER
(R)-3-Methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)...
(R)-(1-Amino-3-methylbutyl)boronic Acid Pinacol Ester Hydrochloride
(R)-1-Amino-3-methylbutan-1-boronic acid pinacol ester hydrochloride
(1R)-3-methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butan-1-amine
(R)-3-Methyl-1-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)butan-1-aMine hydrochloride
(1R)-3-Methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butan-1-amine hydrochloride
(R)-3-Methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butan-1-amine hydrochloride 95+%
(alphaR)-4,4,5,5-Tetramethyl-alpha-(2-methylpropyl)-1,3,2-dioxaborolane-2-methanamine hydrochloride
1,3,2-Dioxaborolane-2-methanamine, 4,4,5,5-tetramethyl-α-(2-methylpropyl)-, hydrochloride (1:1), (αR)-
(alphaR)-4,4,5,5-Tetramethyl-alpha-(2-methylpropyl)-1,3,2-dioxaborolane-2-methanamine hydrochloride (1:1) | [Molecular Formula]
C11H25BClNO2 | [MDL Number]
MFCD26403994 | [MOL File]
1243174-57-3.mol | [Molecular Weight]
249.586 |
| Questions And Answer | Back Directory | [Uses]
(R)-(1-Amino-3-methylbutyl)boronic acid pinacol hydrochloride is a synthetic intermediate for the cancer treatment drug bortezomib. The anticancer effects of bortezomib as a monotherapy have been demonstrated in xenograft models of multiple myeloma, adult leukemia, lung cancer, breast cancer, prostate cancer, pancreatic cancer, head and neck cancer, and colon cancer, as well as in melanoma. |
| Chemical Properties | Back Directory | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [InChI]
InChI=1/C11H24BNO2.ClH/c1-8(2)7-9(13)12-14-10(3,4)11(5,6)15-12;/h8-9H,7,13H2,1-6H3;1H/t9-;/s3 | [InChIKey]
ADICRSVFBDCOLO-OVMXBOEKNA-N | [SMILES]
[C@H](B1OC(C)(C)C(C)(C)O1)(N)CC(C)C.Cl |&1:0,r| |
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