| Identification | Back Directory | [Name]
pirodavir | [CAS]
124436-59-5 | [Synonyms]
R77975
CS-693
R-77975
R 77975
pirodavi
pirodavir
Pirodavir, >=99%
pirodavir(R 77975)
R 77975, Pirodavir
pirodavir USP/EP/BP
R-77975; R77975; R 77975
ethyl p-(2-(1-(6-Methyl-3-pyridazinyl)-4-piperidyl)ethoxy) benzoate
Ethyl 4-[2-[1-(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]benzoate
Ethyl 4-(2-(1-(6-methylpyridazin-3-yl)piperidin-4-yl)ethoxy)benzoate
Ethyl p-[2-[1-(6-Methylpyridazin-3-yl)piperidin-4-yl]-ethoxy]benzoate
4-[2-[1-(6-Methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]benzoic Acid Ethyl Ester
Benzoic acid, 4-[2-[1-(6-Methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]-, ethyl ester | [Molecular Formula]
C21H27N3O3 | [MDL Number]
MFCD00866965 | [MOL File]
124436-59-5.mol | [Molecular Weight]
369.462 |
| Chemical Properties | Back Directory | [Melting point ]
124-125℃ | [storage temp. ]
Sealed in dry,Store in freezer, under -20°C | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
Off-White to Pale Beige | [InChI]
1S/C21H27N3O3/c1-3-26-21(25)18-5-7-19(8-6-18)27-15-12-17-10-13-24(14-11-17)20-9-4-16(2)22-23-20/h4-9,17H,3,10-15H2,1-2H3 | [InChIKey]
KCHIOGFOPPOUJC-UHFFFAOYSA-N | [SMILES]
O=C(OCC)C1=CC=C(OCCC2CCN(C3=NN=C(C)C=C3)CC2)C=C1 |
| Hazard Information | Back Directory | [Description]
Pirodavir is a broad-spectrum antipicornaviral agent.1 It is active against 80 typed (MICs = 0.001-14.4 μg/ml) and one untyped rhinovirus strain (MIC = 0.002 μg/ml) and is active against both group A and group B serotypes. It is also active against serotypes of coxsackievirus, poliovirus, and echovirus enteroviruses (MICs = 0.018-8.5, 0.025-0.27, and 0.019-1.3 μg/ml, respectively). | [Uses]
Pirodavir is used to modulate lipophilicity in human rhinovirus capsid binders. It also is used in order to identify potential ativiral agents.
| [References]
[1] K ANDRIES. In vitro activity of pirodavir (R 77975), a substituted phenoxy-pyridazinamine with broad-spectrum antipicornaviral activity.[J]. Antimicrobial Agents and Chemotherapy, 1992, 36 1: 100-107. DOI: 10.1128/aac.36.1.100 |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
LETOPHARM LIMITED
|
| Telephone: |
+86-21-5821 5861 |
| Website: |
www.letopharm.com |
| Company Name: |
D&C Chemicals
|
| Telephone: |
+86-21-58447131 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList16963/0_EN.htm |
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