| Identification | Back Directory | [Name]
SBFI TETRAAMMONIUM | [CAS]
124549-08-2 | [Synonyms]
SBFI TETRAAMMONIUM
UGJCNRLBGKEGEH-UHFFFAOYSA-N
sodium-bindingbenzofuranisophthalate
1,3-Benzenedicarboxylic acid, 4,4'-[1,4,10-trioxa-7,13-diazacyclopentadecane-7,13-diylbis(5-methoxy-6,2-benzofurandiyl)]bis- | [Molecular Formula]
C44H42N2O15 | [MDL Number]
MFCD00083490 | [MOL File]
124549-08-2.mol | [Molecular Weight]
838.81 |
| Chemical Properties | Back Directory | [Melting point ]
>200℃ | [Boiling point ]
1034.1±65.0 °C(Predicted) | [density ]
1.370±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
Soluble in methanol, dimethyl sulfoxide | [form ]
Solid | [pka]
4.56±0.10(Predicted) | [Appearance]
Solid Powder | [λmax]
339 nm | [Biological Applications]
Sodium indicator; identifying genes; monitoring cellular processes; K+ -channel openers |
| Hazard Information | Back Directory | [Description]
Tetraammonium salt is a cell-impermeant fluorescent sodium indicator. Tetraammonium salt has been used for measurement of intracellular sodium concentrations by ratiometric calculation. | [Uses]
SBFI is a cell-impermeant, fluorescent Na+ indicator dye. SBFI is excited at 340 nm and the fluorophore emission is collected at 450 nm[1]. SBFI selective for Na+ over K+ with Kd values of 20 and 120 mM for these ions, respectively. [2]. | [Definition]
ChEBI: Sodium-binding benzofuran isophthalate is a crown compound that is 1,4,10-trioxa-7,13-diazacyclopentadecane in which the hydrogens of the amino groups at position 7 and 13 are replaced by 2-(2,4-dicarboxyphenyl)-5-methoxy-1-benzofuran-6-yl groups. It is a cell-impermeant fluorescent sodium indicator. It has a role as a fluorochrome. It is a member of 1-benzofurans, a tetracarboxylic acid, a crown compound and an aromatic ether. | [References]
[1] Leeves MA, The effect of mechanical deformation on the distribution of ions in fibroblasts. Am J Orthod Dentofacial Orthop. 1995 Jun;107(6):625-32. DOI:10.1016/s0889-5406(95)70106-0
[2] Minta A, Fluorescent indicators for cytosolic sodium. J Biol Chem. 1989 Nov 15;264(32):19449-57. PMID:2808435 |
|
|