| Identification | Back Directory | [Name]
BCI-215 | [CAS]
1245792-67-9 | [Synonyms]
BCI-215
BCI-215
(BCI215
(E)-2-Benzylidene-5-bromo-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one
1H-Inden-1-one, 5-bromo-3-(cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-, (2E)-
specificity,Phosphatase,DUSP-MKP,inhibit,Inhibitor,MAPK,BCI-215,BCI215,BCI 215,dual | [Molecular Formula]
C22H22BrNO | [MDL Number]
MFCD32644571 | [MOL File]
1245792-67-9.mol | [Molecular Weight]
396.32 |
| Chemical Properties | Back Directory | [Boiling point ]
523.0±50.0 °C(Predicted) | [density ]
1.37±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 33.33 mg/mL (84.10 mM) | [form ]
Solid | [pka]
6.32±0.20(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Definition]
ChEBI: BCI-215 is an aromatic ketone that is 2,3-dihydro-1H-inden-1-one which is substituted at positions 2, 3, and 5 by (E)-benzylidene, cyclohexylamino, and bromine, respectively. A hyperactivator of fibroblast growth factor signaling in transgenic zebrafish that is devoid of developmental toxicity and restores defective MAPK activity caused by overexpression of DUSP1 and DUSP6 in mammalian cells. It has a role as an antineoplastic agent and an apoptosis inducer. It is a secondary amino compound, an aromatic ketone, an organobromine compound, an enone and a member of indanones. |
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