| Identification | Back Directory | [Name]
(25R)-cholest-5-en-26-oic acid, 3,7-hydroxy | [CAS]
1246298-66-7 | [Synonyms]
7-dihydroxy-5-cholestenoic acid
3β,7β-dihydroxy -5-cholestenoic acid
3ss,7ss-dihydroxy-5-cholestenoic acid
(25R)-cholest-5-en-26-oic acid, 3,7-hydroxy
(25R)-cholest-5-en-26-oic acid, 3β,7β-hydroxy
Cholest-5-en-26-oic acid, 3,7-dihydroxy-, (3β,7β,25R)-
(25R) - Cholester-5-ene-26-oleic acid, 3?, 7- hydroxyl
(25R)-CHOLEST-5-EN-26-OIC ACID, 3,7-HYDROXY;3;7-DIHYDROXY-5-CHOLESTENOIC ACID | [Molecular Formula]
C27H44O4 | [MOL File]
1246298-66-7.mol | [Molecular Weight]
432.636 |
| Chemical Properties | Back Directory | [Boiling point ]
588.1±35.0 °C(Predicted) | [density ]
1.12±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
powder | [pka]
4.81±0.21(Predicted) |
| Hazard Information | Back Directory | [Uses]
3β,7β-dihydroxy-5-cholestenoic acid may be used as an authentic diastereoisomer standard in mass spectrometry (MS) experiments. | [General Description]
3β,7β-dihydroxy-5-cholestenoic acid (3β,7β-diHCA) is associated with plasma and is a C27 acid. 3β,7β-diHCA is synthesized from 3β-hydroxy-7-oxocholest-5-en-(25R)26-oic acid (3βH,7O-CA) by the action of the enzyme hydroxysteroid 11-β dehydrogenase 1. | [Biochem/physiol Actions]
3β,7β-dihydroxy-5-cholestenoic acid (3β,7β-diHCA) levels are elevated in Niemann-Pick type C (NPC) disease and Niemann-Pick (NP) disease type B disorders. It elicits toxicity to oculomotor neurons. |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
Creative Enzymes
|
| Tel: |
1-516-855-7709 |
| Website: |
www.creative-enzymes.com |
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