ChemicalBook--->CAS DataBase List--->1246302-93-1

1246302-93-1

1246302-93-1 Structure

1246302-93-1 Structure
IdentificationBack Directory
[Name]

cholest-5-ene-3,22(R)-diol-d7
[CAS]

1246302-93-1
[Synonyms]

22(R)-hydroxycholesterol-d7
cholest-5-ene-3,22(R)-diol-d7
cholest-5-ene-3β,22(R)-diol-d7
CHOLEST-5-ENE-3,22(R)-DIOL-D7;22(R)-HYDROXYCHOLESTEROL-D7
[Molecular Formula]

C27H46O2
[MDL Number]

MFCD22416730
[MOL File]

1246302-93-1.mol
[Molecular Weight]

402.66
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

powder
Hazard InformationBack Directory
[Uses]

lipidomics
metabolomics
[Biological Activity]

22(R)-hydroxycholesterol (22(R)-HC) is a liver X receptor (LXR) ligand and is a key for the receptor activation.. 22(R)-HC promotes mesenchymal stem cell osteogenesis along with other oxysterols. It also regulates cholesterol homeostasis and suppresses prostate tumor progression. Low levels of 22(R)-HC is observed in Alzheimerμs disease and may be implicated in neuroinflammation and neurodegenerative diseases.
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