| Identification | Back Directory | [Name]
25,26,26,26,27,27-hexadeuterocholest-5-ene-3,27-diol | [CAS]
1246302-95-3 | [Synonyms]
26-Hydroxycholesterol-d6
27-Hydroxy Cholesterol-d6
25,26,26,26,27,27-hexadeuterocholest-5-ene-3,27-diol
25,26,26,26,27,27-HEXADEUTEROCHOLEST-5-ENE-3,27-DIOL;27-HYDROXYCHOLESTEROL-D6 | [Molecular Formula]
C27H40D6O2 | [MOL File]
1246302-95-3.mol | [Molecular Weight]
408.69 |
| Hazard Information | Back Directory | [Uses]
27-Hydroxycholesterol-d6 is used in pharmacological studies of cerebral accumulation of dietary derivable plant sterols showing that they do not interfere with memory and anxiety related behaviour in Abcg5-/-mice. | [Biological Activity]
27-hydroxycholesterol is known to induce breast cancer cell proliferation and metastatic progression in experimental models. It might serve as a ligand for liver X receptors (LXR) and farnesoid X-activated receptors (FXRs). 27-hydroxycholesterol controls the action of hydrocymethylglutaryl-CoA reductase. It promotes cholesterol efflux from the vascular endothelium. |
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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