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1246303-20-7

1246303-20-7 Structure

1246303-20-7 Structure
IdentificationBack Directory
[Name]

N-lignoceroyl-ceraMide-1-phosphate (aMMoniuM salt)
[CAS]

1246303-20-7
[Synonyms]

C24 Ceramide-1-Phosphate (d18:1/24:0)
N-lignoceroyl-ceraMide-1-phosphate (aMMoniuM salt)
N-LIGNOCEROYL-CERAMIDE-1-PHOSPHATE (AMMONIUM SALT);C24 CERAMIDE-1-PHOSPHATE (D18:1/24:0)
[Molecular Formula]

C42H87N2O6P
[MDL Number]

MFCD22416609
[MOL File]

1246303-20-7.mol
[Molecular Weight]

747.14
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

powder
Hazard InformationBack Directory
[Uses]

C24 Ceramide-1-Phosphate (d18:1/24:0) or N-lignoceroyl-ceramide-1-phosphate (ammonium salt) has been used as a standard to quantify ceramide content in muscle tissue samples using high-performance liquid chromatography/tandem mass spectrometry (LC/MS2).
[Biological Activity]

Ceramide 1-phosphate (C1P) is a mitogenic agentwhich has antiapoptotic and prosurvival activities. It negatively regulates tumor necrosis factor-α (TNFα) production stimulated by lipopolysaccharide. C1P also mediates inflammatory response and aids in phagocytosis. It is considered as a second lipid messenger of agonist-stimulated sphingomyelin metabolism.
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