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TM38837 is a peripherally selective cannabinoid receptor type 1 (CB1) receptor antagonist. It has limited brain penetration to minimize or prevent CNS adverse effects and retain potential anti-obesity effects. Also it can reduces the propensity for psychotic side effects. | [in vivo]
TM38837 (10-100 mg/kg; po) induces a significant increase in freezing behavior at 100 mg/kg. | Animal Model: | < td class="col2"> 7-8 weeks old male C57BL/6 N mice (B6N) | Dosage: | 10, 30, or 100 mg/kg | | Administration: | po < /td> | | Result: | High dose (100 mg/kg) induced a significant increase in freezing behavior. < /td> | | [target]
| [storage]
Store at -20°C |
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Wuhan Topule
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cjbscvictory
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http://www.weikeqi-biotech.com/ |
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