| Identification | Back Directory | [Name]
MK-7145 | [CAS]
1255204-84-2 | [Synonyms]
MK-7145
1255204-84-2
1(3H)-Isobenzofuranone, 5,5'-[1,4-piperazinediylbis[(1R)-1-hydroxy-2,1-ethanediyl]]bis[4-Methyl-
5,5'-((1R,1'R)-piperazine-1,4-diylbis(1-hydroxyethane-2,1-diyl))bis(4-Methylisobenzofuran-1(3H)-one)
5-[(1R)-1-hydroxy-2-[4-[(2R)-2-hydroxy-2-(4-methyl-1-oxo-3H-2-benzofuran-5-yl)ethyl]piperazin-1-yl]ethyl]-4-methyl-3H-2-benzofuran-1-one | [Molecular Formula]
C26H30N2O6 | [MDL Number]
MFCD22572338 | [MOL File]
1255204-84-2.mol | [Molecular Weight]
466.53 |
| Chemical Properties | Back Directory | [Boiling point ]
750.4±60.0 °C(Predicted) | [density ]
1.342±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
13.63±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
MK-7145 is a ROMK inhibitor, with an IC50 of 0.045 μM. | [storage]
Store at -20°C | [References]
[1] Tang H, et al. Discovery of MK-7145, an Oral Small Molecule ROMK Inhibitor for the Treatment of Hypertension and Heart Failure. ACS Med Chem Lett. 2016 May 12;7(7):697-701. DOI:10.1021/acsmedchemlett.6b00122 |
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| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
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