| Identification | Back Directory | [Name]
1-Piperidinecarboxylic acid, 4-aMino-3,3-difluoro-, 1,1-diMethylethyl ester | [CAS]
1255666-48-8 | [Synonyms]
4-AMino-1-Boc-3,3-difluor...
4-AMino-1-Boc-3,3-difluoropiperidine
1-Boc-4-amino-3,3-difluoropiperidine
1-N-Boc-4-amino-3,3-difluoro-piperidine
tert-butyl 4-amino-3,3-difluoropiperidin
tert-butyl 4-aMino-3,3-difluoropiperidine-1-carboxylate
4-Amino-3,3-difluoro-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
1-Piperidinecarboxylic acid, 4-aMino-3,3-difluoro-, 1,1-diMethylethyl ester | [Molecular Formula]
C10H18F2N2O2 | [MDL Number]
MFCD16250242 | [MOL File]
1255666-48-8.mol | [Molecular Weight]
236.26 |
| Chemical Properties | Back Directory | [Boiling point ]
281.5±40.0 °C(Predicted) | [density ]
1.17±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [pka]
7.66±0.40(Predicted) | [Appearance]
Off-white to yellow Solid | [InChI]
InChI=1S/C10H18F2N2O2/c1-9(2,3)16-8(15)14-5-4-7(13)10(11,12)6-14/h7H,4-6,13H2,1-3H3 | [InChIKey]
APZOOTJWPGQYSZ-UHFFFAOYSA-N | [SMILES]
N1(C(OC(C)(C)C)=O)CCC(N)C(F)(F)C1 |
| Hazard Information | Back Directory | [Uses]
1-(tert-Butyloxycarbonyl)-3,3-difluoro-4-aminopiperidine is synthetic building block for pharmaceuticals. It can be obtained from N-Benzyl-β-alanine Ethyl Ester (B232975) which is used as a reagent in organic synthesis including that of dipivaloyloxyphenyl aminopropionate β-agonist prodrugs which are used in the treatment of psoriasis. N-Benzyl-β-alanine Ethyl Ester (B232975) is also used in the synthesis of N,N'-dithiobis(N-benzyl-β-alanine) dethyl ester, which is an important intermediate of insecticide OK-135, and in synthesis of spiropiperidine-based orexin-2 receptor (OX2R) antagonists. |
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Jia Xing Isenchem Co.,Ltd
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https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
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Cochemical Ltd.
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029-86115547 17791676824 |
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Cool Pharm, Ltd
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021-60455363 18019463053 |
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NovoChemy Ltd.
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86-(0)21-31261262 373522135 |
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SPIRO PHARMA
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www.spiropharma.com.cn |
| Company Name: |
Cochemical Ltd.
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029-86115547 17791676824 |
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http://www.cochemical.com |
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Wuxi AppTec
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022-59987777 13552403979 |
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