ChemicalBook--->CAS DataBase List--->1256493-34-1

1256493-34-1

1256493-34-1 Structure

1256493-34-1 Structure
IdentificationBack Directory
[Name]

2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide
[CAS]

1256493-34-1
[Synonyms]

Dyng
o-4a
Dyngo-4a
Dyngo-49
Hydroxy-Dynasore
3-Hydroxy-N′-[(2,4,5-trihydroxyphenyl)methylidene]naphthalene-2-carbohydrazide
3-Hydroxy-2-naphthalenecarboxylic acid 2-[(2,4,5-trihydroxyphenyl)methylene]hydrazide
3-Hydroxynaphthalene-2-carboxylic acid 2-[(2,4,5)-trihydroxyphenyl)methylene]hydrazide
2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide
[Molecular Formula]

C18H14N2O5
[MDL Number]

MFCD23704787
[MOL File]

1256493-34-1.mol
[Molecular Weight]

338.31
Chemical PropertiesBack Directory
[density ]

1.45±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO: >10mg/mL
[form ]

powder
[pka]

8.28±0.40(Predicted)
[color ]

faint yellow to dark yellow
Safety DataBack Directory
[Hazard Codes ]

N
[Risk Statements ]

50
[Safety Statements ]

61
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Hydroxy-Dynasore is an inhibitor of dynamin I and dynamin II.
[Definition]

ChEBI: Dyngo-4a is dynamin inhibitor. It has a role as an EC 3.6.5.5 (dynamin GTPase) inhibitor.
[Biochem/physiol Actions]

Hydroxy-Dynasore is a cell permeable and potent dynamin inhibitor that prevents uptake of recombinant botulinum neurotoxin A heavy chain binding domain (BoNT/A-Hc). Apparently, Hydroxy-Dynasore prevents dynamin-mediated fission of endocytic vesicles from the plasma membrane.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide(1256493-34-1)MS
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