| Identification | Back Directory | [Name]
CGP 31358 | [CAS]
125652-47-3 | [Synonyms]
CGP 31358
1H-1,2,4-Triazole-3-carboxamide, 1-[4-[1-(4-chlorophenyl)-1-methylethyl]-2-methoxyphenyl]- | [Molecular Formula]
C19H19ClN4O2 | [MOL File]
125652-47-3.mol | [Molecular Weight]
370.83 |
| Hazard Information | Back Directory | [Uses]
CGP 31358 is an anticonvulsant agent that binds to a site on the NMDA receptor complex that is coupled to both the transmitter recognition site and to the channel domain. CGP 31358 inhibits the binding of L-Glutamate to the NMDA receptor complex with an IC50 of 53 μM[1]. | [IC 50]
NMDA Receptor | [References]
[1] J Baud, et al. CGP 31358 binds to a site on the NMDA receptor that is coupled to both the transmitter recognition site and the channel domain. Neurosci Lett. 1989 Dec 15;107(1-3):184-8. DOI:10.1016/0304-3940(89)90814-8 |
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