ChemicalBook--->CAS DataBase List--->125678-68-4

125678-68-4

125678-68-4 Structure

125678-68-4 Structure
IdentificationBack Directory
[Name]

MYRISTOYL-LYS-ARG-THR-LEU-ARG-OH
[CAS]

125678-68-4
[Synonyms]

N-M-KRTLR
MYRISTOYL-KRTLR-OH
MYRISTOYL-LYS-ARG-THR-LEU-ARG
MYRISTOYL-LYS-ARG-THR-LEU-ARG-OH
N-MYRISTOYL-LYS-ARG-THR-LEU-ARG-OH
29:PN:WO2011083481 SEQID:29 claimed protein
MYRISTOYL-LYS-ARG-THR-LEU-ARG: MYRISTOYL-KRTLR
n-myristoyl-lysyl-arginyl-threonyl-leucyl-arginine
L-Arginine, N2-(1-oxotetradecyl)-L-lysyl-L-arginyl-L-threonyl-L-leucyl-
[Molecular Formula]

C42H82N12O8
[MDL Number]

MFCD00238307
[MOL File]

125678-68-4.mol
[Molecular Weight]

883.18
Chemical PropertiesBack Directory
[storage temp. ]

-15°C
Hazard InformationBack Directory
[Uses]

N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor with an IC50 value of 75 μM. N-Myristoyl-Lys-Arg-Thr-Leu-Arg inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat[1].
[References]

[1] Ioannides CG, et, al. Inhibition of IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat by a novel peptide inhibitor of protein kinase C. Cell Immunol. 1990 Nov;131(1):242-52. DOI:10.1016/0008-8749(90)90250-u
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