| Hazard Information | Back Directory | [Description]
A-1211212 is a BCL-2 inhibitor. A-1211212 positively altered the colonic mucosa and ameliorated inflammation in mice. Pro-apoptotic BCL-2 inhibitor A-1211212 diminishes lymphocytes and ameliorates colitis in Il10-/- mice without inducing thrombocytopenia. | [Uses]
A-1211212 (BCL2-IN-1) is a potent Bcl-2 inhibitor. BCL2-IN-1 binds Bcl-2 with a Ki of <0.01 nM[1]. | [References]
[1] Nathaniel D. Catron, et al. Solid dispersions containing an apoptosis-inducing agent. WO2012058392A1. |
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