| Identification | Back Directory | [Name]
2,6-dimethyl-4-(2-(4-fluorophenyl)ethenyl)phenol | [CAS]
125722-16-9 | [Synonyms]
BIL-239
2,6-dimethyl-4-(2-(4-fluorophenyl)ethenyl)phenol
4-[(E)-2-(4-Fluorophenyl)ethenyl]-2,6-dimethylphenol
Phenol, 4-[(1E)-2-(4-fluorophenyl)ethenyl]-2,6-dimethyl- | [Molecular Formula]
C16H15FO | [MOL File]
125722-16-9.mol | [Molecular Weight]
242.29 |
| Hazard Information | Back Directory | [Description]
BI-L 239 inhibits 5-lipoxygenase products that cause bronchoconstriction. | [Uses]
Enofelast (BI-L-239), a 5-lipoxygenase (5-LO) inhibitor, exhibits an IC50 of 2.48 μM for inhibition of calcium ionophore-induced LTB4 generation[1]. | [References]
[1] T C Noonan, et al. Effect of BI-L-239, A-64077 and MK-886 on leukotriene B4 synthesis by chopped guinea pig lung and on antigen-induced tracheal contraction in vitro. Prostaglandins. 1992 Dec;44(6):543-54. DOI:10.1016/0090-6980(92)90024-n |
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