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126-52-3

126-52-3 Structure

126-52-3 Structure
IdentificationBack Directory
[Name]

ETHINAMATE
[CAS]

126-52-3
[Synonyms]

Valmid
Valamin
Volamin
Valamina
Valmidate
Etinamate
usafel-42
Ethinamat
Ethinimate
ETHINAMATE
USAF el-42
valaminetta
Valaminettae
Valaminetten
ETHINAMATE USP/EP/BP
ethynylcyclohexylcarbamate
GXRZIMHKGDIBEW-UHFFFAOYSA-N
1-ethinylcyclohexylcarbamate
1-ethinylcyclohexylcarbonate
1-ethynylcyclohexylcarbamate
Aethinyl-cyclohexyl-carbamat
1-Ethynylcyclohexyl carbamate
1-Ethinylcyclohexyl carbamate
1-ethynyl-cyclohexanocarbamate
1-ETHYNYLCYCLOHEXANOL CARBAMATE
carbamatedel’ethinylcyclohexanol
ethinamate--dea schedule iv item
Carbamate de L'ethinylcyclohexanol
Cyclohexanol, 1-ethynyl-, carbamate
carbamicacid1-ethynylcyclohexylester
carbamicacid,1-ethynylcyclohexylester
Cyclohexanol, 1-ethynyl-, 1-carbamate
Carbamic acid, 1-ethynylcyclohexyl ester
[EINECS(EC#)]

204-789-4
[Molecular Formula]

C9H13NO2
[MDL Number]

MFCD00063343
[MOL File]

126-52-3.mol
[Molecular Weight]

167.21
Chemical PropertiesBack Directory
[Melting point ]

96-98°
[Boiling point ]

bp3 118-122°
[density ]

1.1222 (rough estimate)
[refractive index ]

nD21.5 1.4441 (20% in propylene glycol)
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

neat
[pka]

13.40±0.50(Predicted)
[EPA Substance Registry System]

Cyclohexanol, 1-ethynyl-, carbamate (126-52-3)
Hazard InformationBack Directory
[Definition]

ChEBI: A carbamate ester that is the 1-vinylcyclohexyl ester of carbamic acid. A short-acting sedative-hypnotic, it was formerly used to treat insomnia.
[Originator]

Valmid,Dista,US,1955
[Uses]

Ethinamate (E890730) is a an active central nervous system depressant used in the treatment of insomnia.
[Manufacturing Process]

A solution of 34 cc (0.5 mol) of liquid phosgene in 150 cc of absolute ether is reacted while cooling with a mixture of sodium chloride and ice, first with 62 grams (0.5 mol) of 1-ethinyl cyclohexanol-1 and then with 64 cc (0.5 mol) of quinoline. The precipitated quinoline chlorohydrate is filtered off and the filtrate is reacted with ammonia in ether. In this manner 45 grams of the carbamic acid ester of 1-ethinyl cyclohexanol are obtained. Yield: 53% of the theoretical yield. The ester boils at 108° to 110°C/3 mm and on recrystallization from cyclohexane, yields colorless needles melting at 94° to 96°C.
[Therapeutic Function]

Sedative
Safety DataBack Directory
[Hazard Codes ]

T,Xn
[Risk Statements ]

23/24/25-22
[Safety Statements ]

22-36/37/39-45
[RTECS ]

GV9275000
[TSCA ]

TSCA listed
[Safety Profile]

A deadly human poison. Experimental poison by ingestion, intravenous, subcutaneous, and intraperitoneal routes. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx. See also CARBAMATES.
[Hazardous Substances Data]

126-52-3(Hazardous Substances Data)
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