Identification | Back Directory | [Name]
CBZ-AEA | [CAS]
1260092-43-0 | [Synonyms]
CBZ-AEA CBZ-NH-PEG1-COOH CBZ-NH-PEG1-acetic acid MBFFUILDSABICM-UHFFFAOYSA-N 2-[2-(Cbz-amino)ethoxy]acetic acid 2-[2-(benzyloxycarbonylamino)ethoxy]aceticacid Acetic acid, 2-[2-[[(phenylmethoxy)carbonyl]amino]ethoxy]- 2-(2-(((Benzyloxy)carbonyl)amino)ethoxy)acetic acid[2-[2-(Cbz-amino)ethoxy]acetic acid | [Molecular Formula]
C12H15NO5 | [MDL Number]
MFCD21933598 | [MOL File]
1260092-43-0.mol | [Molecular Weight]
253.25 |
Chemical Properties | Back Directory | [Boiling point ]
481.1±35.0 °C(Predicted) | [density ]
1.256±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
Solid | [pka]
3.44±0.10(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
Cbz-NH-PEG1-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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