ChemicalBook--->CAS DataBase List--->1260092-43-0

1260092-43-0

1260092-43-0 Structure

1260092-43-0 Structure
IdentificationBack Directory
[Name]

CBZ-AEA
[CAS]

1260092-43-0
[Synonyms]

CBZ-AEA
CBZ-NH-PEG1-COOH
CBZ-NH-PEG1-acetic acid
MBFFUILDSABICM-UHFFFAOYSA-N
2-[2-(Cbz-amino)ethoxy]acetic acid
2-[2-(benzyloxycarbonylamino)ethoxy]aceticacid
Acetic acid, 2-[2-[[(phenylmethoxy)carbonyl]amino]ethoxy]-
2-(2-(((Benzyloxy)carbonyl)amino)ethoxy)acetic acid[2-[2-(Cbz-amino)ethoxy]acetic acid
[Molecular Formula]

C12H15NO5
[MDL Number]

MFCD21933598
[MOL File]

1260092-43-0.mol
[Molecular Weight]

253.25
Chemical PropertiesBack Directory
[Boiling point ]

481.1±35.0 °C(Predicted)
[density ]

1.256±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[form ]

Solid
[pka]

3.44±0.10(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P312-P351
Hazard InformationBack Directory
[Uses]

Cbz-NH-PEG1-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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