| Identification | Back Directory | [Name]
H-GLY-PRO-ARG-PRO-NH2 | [CAS]
126047-75-4 | [Synonyms]
GPRP-NH2
H2N-GPRP-AMIDE
Gly-Pro-Arg-Pro-NH2
gly-pro-arg-pro amide
H-GLY-PRO-ARG-PRO-NH2
GLY-PRO-ARG-PRO AMIDE PEPTIDE
gly-pro-arg-pro amide acetate
H-Gly-Pro-Arg-Pro-NH2/GPRP-NH2
H-Gly-Pro-Arg-Pro-NH acetate salt
H-Gly-Pro-Arg-Pro-NH2 acetate salt
Gly-Pro-Arg-Pro amide >=97% (HPLC)
Glycyl-L-prolyl-L-arginyl-L-prolinamide
L-Prolinamide, glycyl-L-prolyl-L-arginyl- | [Molecular Formula]
C18H32N8O4 | [MDL Number]
MFCD00237962 | [MOL File]
126047-75-4.mol | [Molecular Weight]
424.5 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [Sequence]
Gly-Pro-Arg-Pro-NH2 | [InChIKey]
SCCTZYGEMPQRCV-AVGNSLFASA-N | [SMILES]
NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N2CCC[C@H]2C(N)=O |
| Hazard Information | Back Directory | [Uses]
Gly-Pro-Arg-Pro amide has been used-
- as a constituent of buffer during fluid-phase and bound thrombin inhibition assays, to determine the activity of thrombin
- for blocking fibrin polymerization and preventing fibrin clot formation in presence of α-thrombin, in blood obtained from mice
- during preparation of human soluble fibrin, to block the polymerization of soluble fibrin
| [General Description]
Gly-Pro-Arg-Pro is a peptide that mimics the N-terminal Gly-Pro-Arg region in the a chain of fibrin protein. | [Biochem/physiol Actions]
Gly-Pro-Arg-Pro peptide suppresses the early steps of fibrin polymerization. The amide derivative of this peptide prevents the degradation of fibrinogen and fragment D by plasmin, even in the presence of EGTA (ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid). |
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| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
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