ChemicalBook--->CAS DataBase List--->1260643-32-0

1260643-32-0

1260643-32-0 Structure

1260643-32-0 Structure
IdentificationBack Directory
[Name]

6-BROMO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-1-CARBOXYLIC ACID
[CAS]

1260643-32-0
[Synonyms]

6-BROMO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-1-CARBOXYLIC ACID
1-Isoquinolinecarboxylic acid, 6-bromo-1,2,3,4-tetrahydro-
[Molecular Formula]

C10H10BrNO2
[MDL Number]

MFCD04114846
[MOL File]

1260643-32-0.mol
[Molecular Weight]

256.1
Chemical PropertiesBack Directory
[Boiling point ]

415.6±45.0 °C(Predicted)
[density ]

1.593±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[pka]

1.71±0.20(Predicted)
Questions And AnswerBack Directory
[Uses]

6-Bromo-1,2,3,4-Tetrahydroisoquinoline-1-carboxylic acid, as an important tetrahydroisoquinoline derivative, is used in the manufacture of highly effective insecticides, color films and dyes, and also has important pharmacological effects, such as vasodilatory, antitumor, antihypertensive, antiarrhythmic, and antithrombotic activities.
Hazard InformationBack Directory
[Synthesis]

In a three-necked flask, 200mL of tetrahydrofuran, 35.0g of methyl 3-bromophenyl ethylcarbamate and 50mL of concentrated sulfuric acid were added, and the reaction was heated to reflux. At the end of the reaction, it was poured into 500mL of ice water,

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