1261079-38-2

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1261079-38-2 Structure

Identification	Back Directory
[Name] NALOXONE-D5
[CAS] 1261079-38-2
[Synonyms] Nalone-d5 Narcan-d5 Narcanti-d5 NALOXONE-D5 EN-15304-d5 Naloxone-d5 (CRM) Naloxone-D5 solution 17-Allyl-4,5a-epoxy-3,14-dihydroxymorphinan-6-one-d5 Hydrochloride 17-Allyl-4,5α-epoxy-3,14-dihydroxyMorphinan-6-one-d5 Hydrochloride 5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl-d5)Morphinan-6-one Hydrochloride 5a)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl-d5)morphinan-6-one Hydrochloride
[EINECS(EC#)] 200-659-6
[Molecular Formula] C19H16D5NO4
[MDL Number] MFCD08063611
[MOL File] 1261079-38-2.mol
[Molecular Weight] 332.41

Chemical Properties	Back Directory
[Appearance] Crystalline Solid
[Melting point ] 200-2050C
[Fp ] 9℃
[storage temp. ] -20°C Freezer
[solubility ] Chloroform (Slightly), Methanol (Slightly)
[form ] Solid
[color ] White to Off-White

Hazard Information	Back Directory
[Chemical Properties] Crystalline Solid
[Uses] Labelled specific opioid antagonist. Narcotic antagonist. Intended for use as an internal standard for the quantification of Naloxone by GC- or LC-mass spectrometry.
[Description] Naloxone-d₅ (CRM) (Item No. 18274) is a certified reference material intended for use as an internal standard for the quantification of naloxone (Item Nos. ISO60191 \| 15594) by GC- or LC-MS. Naloxone is categorized as an opioid antagonist. Formulations containing naloxone have been used as antidotes for opioid overdose and the prevention of overdose. They have also been used in combination with buprenorphine (Item Nos. ISO60178 \| 14025) in the treatment of opiate addiction and in pain management. This product is intended for research and forensic applications.
[References] [1] BERTRAND LE BOURDONNEC . Novel trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines as μ opioid receptor antagonists with improved opioid receptor selectivity profiles[J]. Bioorganic & Medicinal Chemistry Letters, 2008, 18 6: Pages 2006-2012. DOI: 10.1016/j.bmcl.2008.01.106

Safety Data	Back Directory
[Hazard Codes ] F,T
[Risk Statements ] 11-23/24/25-39/23/24/25
[Safety Statements ] 7-16-36/37-45
[RIDADR ] UN1230 - class 3 - PG 2 - Methanol, solution
[WGK Germany ] 1

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