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126139-44-4

126139-44-4 Structure

126139-44-4 Structure
IdentificationBack Directory
[Name]

2’-Deoxy-2’-(N-trifluoroacetyl)amino-5’-O-DMTr-uridine 3’-CED phosphoramidite
[CAS]

126139-44-4
[Synonyms]

2’-Deoxy-2’-(N-trifluoroacetyl)amino-5’-O-DMTr-uridine3’-CEDphosphoramidite
2’-Deoxy-2’-(N-trifluoroacetyl)amino-5’-O-DMTr-uridine 3’-CED phosphoramidite
Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-[(2,2,2-trifluoroacetyl)amino]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
[Molecular Formula]

C41H47F3N5O9P
[MDL Number]

MFCD16876404
[MOL File]

126139-44-4.mol
[Molecular Weight]

841.81
Chemical PropertiesBack Directory
[Melting point ]

240-243 °C(Solv: ethanol (64-17-5))
[pka]

8.94±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

2’-Deoxy-2’-(N-trifluoroacetyl)amino-5’-O-DMTr-uridine 3’-CED phosphoramidite is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].
[References]

[1] Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25. DOI:10.1016/s0165-6147(99)01298-5
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