| Identification | Back Directory | [Name]
2-BenzothiazolaMine, N-propyl-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]- | [CAS]
1262406-02-9 | [Synonyms]
JNK-1-IN-1
N-propyl-N-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-benzothiazol-2-amine
2-BenzothiazolaMine, N-propyl-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]- | [Molecular Formula]
C24H22N6S | [MOL File]
1262406-02-9.mol | [Molecular Weight]
426.537 |
| Hazard Information | Back Directory | [Uses]
JNK-1-IN-1 is a JNK-1 inhibitor. JNK-1-IN-1 also inhibits MKK7 with an IC50 of 7.8μM. JNK-1-IN-1 bind to MKK7cp and acts as an inhibitor of JNK-1[1]. | [IC 50]
JNK1 | [References]
[1] Comess KM, et al. Discovery and characterization of non-ATP site inhibitors of the mitogen activated protein (MAP) kinases. ACS Chem Biol. 2011 Mar 18;6(3):234-44. DOI:10.1021/cb1002619 |
|
|