| Identification | Back Directory | [Name]
DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE | [CAS]
126429-21-8 | [Synonyms]
DIALLYL DIISOPROPYLPHOSPHORAMIDITE
Diallyloxy(diisopropylamino)phosphine
DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE
N-bis(prop-2-enoxy)phosphanyl-N-propan-2-ylpropan-2-amine
N,N-Bis(1-methylethyl)phosphoramidous acid di-2-propenyl ester
Phosphoramidous acid, N,N-bis(1-methylethyl)-, di-2-propen-1-yl ester | [Molecular Formula]
C12H24NO2P | [MDL Number]
MFCD00216647 | [MOL File]
126429-21-8.mol | [Molecular Weight]
245.3 |
| Chemical Properties | Back Directory | [Boiling point ]
130 °C(lit.)
| [density ]
0.928 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.456(lit.)
| [Fp ]
90 °F
| [storage temp. ]
2-8°C
| [pka]
4.96±0.70(Predicted) | [BRN ]
4383514 |
| Questions And Answer | Back Directory | [Phophorylating Reagent]
Diallyl N,N-diisopropylphosphoramidite was employed as a phophorylating reagent. It can be used for reactions involved in phosphitylation of alcohols, deallylation for the synthesis of nucleoside phosphoramidite, posphitylation and stereoselective pudovik rearrangement. It can be used for preparation of peptide substrates, rhodamine dyes with phosphorylated CH2OH sites, and 3-[4-(bis-allyloxy- phosphoryloxy)-2(R)-hydroxy-3,3-dimethyl-butyrylamino]-thiopropionic acid-S-propylester and so on. It also involved in the synthesis of pharmacologically active molecules including selective orally active S1P1 agonists, water-soluble prodrugs of triazole CS-758 with antifungal activity, and fostriecin analogs as antitumor agents, and so on
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| Hazard Information | Back Directory | [Uses]
Precursor involved in the synthesis of pharmacologically active molecules including:• ;Selective orally active S1P1 agonists1• ;Water-soluble prodrugs of triazole CS-758 with antifungal activity2• ;Fostriecin analogs as antitumor agents3Reactant involved in: • ;Phosphitylation of alcohols4• ;Deallylation for the synthesis of nucleoside phosphoramidite5• ;Posphitylation and stereoselective Pudovik rearrangement6 |
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Shureli Biopharma Co.,Ltd Gold
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Energy Chemical
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Mashilabs (Shanghai) Co.,Ltd.
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