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126876-64-0

126876-64-0 Structure

126876-64-0 Structure
IdentificationBack Directory
[Name]

NALTRINDOLE ISOTHIOCYANATE
[CAS]

126876-64-0
[Synonyms]

NALTRINDOLE ISOTHIOCYANATE
naltrindole 5'-isothiocyanate
NALTRINDOLE ISOTHIOCYANATE SELECTIVE DEL TA 2 OPI
4,8-Methanobenzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol, 7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-11-isothiocyanato-, (4bS,8R,8aS,14bR)-
[Molecular Formula]

C27H25N3O3S
[MDL Number]

MFCD00153846
[MOL File]

126876-64-0.mol
[Molecular Weight]

471.57
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 3.3 mg/mL
[form ]

solid
[color ]

off-white
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Naltrindole 5′-isothiocyanate (5'-NTII) is a non-selective delta opioid receptor antagonist that can antagonize the analgesic effects induced by DSLET (HY-P1332) without affecting the analgesic effects induced by DPDPE (HY-P1334)[1].
[References]

[1] S Chakrabarti, et al. Differential antagonism by naltrindole-5'-isothiocyanate on [3H]DSLET and [3H]DPDPE binding to striatal slices of mice. Life Sci. 1993;53(23):1761-5. DOI:10.1016/0024-3205(93)90163-w
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