| Identification | Back Directory | [Name]
1,2,15,16-tetrahydrotanshiquinone | [CAS]
126979-84-8 | [Synonyms]
Trijuganone B
Tetrahydro tanshinone I
1,2,15,16-tetrahydrotanshiquinone
Phenanthro[1,2-b]furan-10,11-dione, 1,2,8,9-tetrahydro-1,6-dimethyl-, (1R)- | [Molecular Formula]
C18H16O3 | [MOL File]
126979-84-8.mol | [Molecular Weight]
280.32 |
| Chemical Properties | Back Directory | [Boiling point ]
470.0±45.0 °C(Predicted) | [density ]
1.29±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder | [color ]
Red |
| Hazard Information | Back Directory | [Description]
Tetrahydrotanshinone I is one compound of Fufang Danshen Prescription (FDP) , liposome equilibrium dialysis system could simply and effectively esti-mate the absorption of multiple components in FDP in vivo, and predicts the potential bioactivity of these components, and thus contributes to the investigation of bioactive compounds with curative effect in FDP. | [Uses]
Trijuganone B (Tetrahydro tanshinone I) can be extracted from from the roots of Salvia miltiorrhiza f. alba. Trijuganone B inhibits the proliferation of leukemia cells[1][2]. | [References]
[1] Zhu Z, et al. Rapid separation and identification of phenolic and diterpenoid constituents from Radix Salvia miltiorrhizae by high-performance liquid chromatography diode-array detection, electrospray ionization time-of-flight mass spectrometry and electrospray ionization quadrupole ion trap mass spectrometry. Rapid Commun Mass Spectrom. 2007;21(12):1855-65. DOI:10.1002/rcm.3023
[2] Uto T, et al. Antiproliferative activity and apoptosis induction by trijuganone C isolated from the root of Salvia miltiorrhiza Bunge (Danshen). Phytother Res. 2018 Apr;32(4):657-666. DOI:10.1002/ptr.6013 |
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