| Identification | Back Directory | [Name]
compound 348U87 | [CAS]
127142-14-7 | [Synonyms]
compound 348U87
Carbonothioic dihydrazide, 2-[[(2-chlorophenyl)amino]thioxomethyl]-2'-[1-(2-pyridinyl)ethylidene]- | [Molecular Formula]
C15H15ClN6S2 | [MOL File]
127142-14-7.mol | [Molecular Weight]
378.9 |
| Hazard Information | Back Directory | [Uses]
BW 348U87 is an inhibitor for ribonucleotide reductase, which exhibits synergistic effect with Acyclovir (HY-17422), potentiate the antiviral activity of Acyclovir against herpes simplex virus (HSV) in athymic nude mouse model[1]. | [References]
[1] Spector T, et al., Inactivators of herpes simplex virus ribonucleotide reductase: hematological profiles and in vivo potentiation of the antiviral activity of acyclovir. Antimicrob Agents Chemother. 1992 May;36(5):934-7. DOI:10.1128/AAC.36.5.934 |
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