| Identification | Back Directory | [Name]
PANTOPRAZOLE SULPHONE SODIUM SALT | [CAS]
127780-16-9 | [Synonyms]
Pantoprazole-1 Pantoprazole RC A Pantoprazole Sulphone Pantoprazole Ep Imp A Pantoprazole EP IMpurity A Pantoprazole sodium impurity A Pantoprazole Related CoMpound A PANTOPRAZOLE SULPHONE SODIUM SALT Pantoprazole sulfone (impurity A) Pantoprazole Sodium EP Impurity A Pantoprazole Sulphone (IMpurity A) Pantoprazole USP Related Compound A 5-(Difluoromethoxy)-2-[[(3,4-dimeth Pantoprazole Sodium Sesquihydrate Impurity A Pantoprazole Sodium Sesquihydrate EP Impurity A Pantoprazole EP Impurity A (Pantoprazole Sulphone) Pantoprazole Impurity 1(Pantoprazole EP Impurity A) Pantoprazole EP IMpurity-A (PantoprazoleSulfone) (USP RC A) 5-difluoromethoxy-2-((3,4 dimethoxy-2-pyridyl)methylsulfonyl)-1H-benzimidazole 5-Difluoromethoxy-2-[[(3,4-dimethoxy)-2-pyridyl]methylsulfonyl]-1H-benzimidazol 5-(Difluoromethoxy)-1H-benzimidazole-2-yl(3,4-dimethoxy-2-pyridylmethyl) sulfone 5-DIFLUOROMETHOXY-2-[( 3,4-DIMETHOXY-2-PYRIDINYLMETHYL SULFONYL) -1H-BENZIMIDAZOLE 6-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfonyl]-1H-benzimidazole Pantoprazole EP Impurity A/ Pantoprazole Related Compound A (Pantoprazole Sulfone) 5-(Difluoromethoxy)-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]sulfone}-1H-benzimidazole 5-(Difluoromethoxy)-2-[[(3,4-dimethoxypyridin-2-yl)methyl]sulfonyl]-1H-benzimidazole [(3,4-Dimethoxypyridin-2-yl)methyl][5-(difluoromethoxy)-1H-benzimidazol-2-yl] sulfone 1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfonyl]- 5-(difluoromethoxy)-2-(((3,4-dimethoxypyridin-2-yl)methyl)sulfonyl)-1H-benzo[d]imidazole 6-(Difluoromethoxy)-2-(((3,4-dimethoxypyridin-2-yl)methyl)sulfonyl)-1H-benzo[d]imidazole Pantoprazole Related Compound A (5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfonyl (1494909) 6-(Difluoromethoxy)-2-(((3,4-dimethoxypyridin-2-yl)methyl)sulfonyl)-1H-benzo[d]imidazole (Pantoprazole Impurity) Pantoprazole Related Compound A (25 mg) (5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole) Pantoprazole impurity 1/Pantoprazole EP Impurity A/Pantoprazole Sulphone/6-(difluoromethoxy)-2-(((3,4-dimethoxypyridin-2-yl)methyl)sulfonyl)-1H-benzo[d]imidazole Pantoprazole EP impurity AQ: What is
Pantoprazole EP impurity A Q: What is the CAS Number of
Pantoprazole EP impurity A Q: What is the storage condition of
Pantoprazole EP impurity A Q: What are the applications of
Pantoprazole EP impurity A | [Molecular Formula]
C16H14F2N3NaO5S | [MDL Number]
MFCD08063689 | [MOL File]
127780-16-9.mol | [Molecular Weight]
421.35 |
| Chemical Properties | Back Directory | [Melting point ]
145-150℃ | [Boiling point ]
586.3±60.0 °C(Predicted) | [density ]
1.457±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 5 mg/ml | [form ]
neat | [pka]
7.40±0.10(Predicted) | [BRN ]
9430498 | [Major Application]
pharmaceutical (small molecule) | [InChI]
1S/C16H15F2N3O5S/c1-24-13-5-6-19-12(14(13)25-2)8-27(22,23)16-20-10-4-3-9(26-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21) | [InChIKey]
FCJYMBZQIJDMMM-UHFFFAOYSA-N | [SMILES]
FC(F)Oc1cc2nc([nH]c2cc1)[S](=O)(=O)Cc3nccc(c3OC)OC |
| Hazard Information | Back Directory | [Chemical Properties]
Brown to Purple Solid | [Uses]
A metabolite of Pantoprazole (P183000), an antiulcerative, gastric pump inhibitor. | [Definition]
ChEBI: 1H-Benzimidazole, 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfonyl]- is a member of benzimidazoles and a sulfoxide. | [Synthesis]
Pantoprazole impurity A was prepared as follows: 237 mg (815 μmol) of S-dichloro chiral ligand, 95.8 mg (271 μmol) of ferric triacetylacetonate (Iron(III) acetylacetonate), and the lithium salt of 4-dimethylamino benzoic acid, 23.4 mg (137 μmol), were sus |
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