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1281872-58-9

1281872-58-9 Structure

1281872-58-9 Structure
IdentificationBack Directory
[Name]

2,3-Dihydro-α-methyl-6-benzofuranethanamine Hydrochloride
[CAS]

1281872-58-9
[Synonyms]

6-APDB (hydrochloride)
6-(2-AMINOPROPYL)-2,3-DIHYDROBENZOFURAN HCL
1-(benzofuran-6-yl)propan-2-aminehydrochloride
2,3-Dihydro-α-methyl-6-benzofuranethanamine Hydrochloride
[Molecular Formula]

C11H16ClNO
[MDL Number]

MFCD18904324
[MOL File]

1281872-58-9.mol
[Molecular Weight]

213.71
Chemical PropertiesBack Directory
[solubility ]

DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 1 mg/ml
[form ]

A crystalline solid
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302+H312+H332
[Precautionary statements ]

P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P321-P330-P362+P364-P501
Hazard InformationBack Directory
[Description]

6-APDB, known more formally as 2,3-dihydro-α-methyl-6-benzofuranethanamine, is an analog of the psychedelic drugs MDA and 6-APB. This compound fully substitutes for the entactogen MBDB in animal drug-discrimination studies and blocks the reuptake of serotonin (IC50 = 322 nM) more potently than dopamine and norepinephrine (IC50s = 1,997 and 980 nM, respectively) by rat synaptosomes. This product is intended for forensic and research applications.
[Uses]

2,3-Dihydro-α-methyl-6-benzofuranethanamine Hydrochloride is a stimulant and entactogen drug of phenethylamine and amphetamine classes. 2,3-Dihydro-α-methyl-6-benzofuranethanamine Hydrochloride is als o an analog of 3,4-Methylenedioxyamphetamine (M303965), a psychedlic drug that exhibits inhibitory actions towards the reuptake of serotonin.
[References]

[1] A. P. MONTE. ChemInform Abstract: Synthesis and Pharmacological Examination of Benzofuran, Indan, and Tetralin Analogues of 3,4-(Methylenedioxy)amphetamine.[J]. ChemInform, 1994, 25 13. DOI: 10.1002/chin.199413160
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