ChemicalBook--->CAS DataBase List--->128201-89-8

128201-89-8

128201-89-8 Structure

128201-89-8 Structure
IdentificationBack Directory
[Name]

4-[[(5Z,8Z,11Z,14Z)-1-OXO-5,8,11,14-EICOSATETRAENYL]AMINO]BUTANOIC ACID
[CAS]

128201-89-8
[Synonyms]

NAGABA
N-ARACHIDONYLGABA
N-ArachidonoylGABA
N-Arachidonoyl-GABA (NA-GABA)
N-Arachidonoyl-γ-Aminobutyric Acid
NArachidonylGABA,N ArachidonylGABA
N-ARACHIDONOYL-GAMMA-AMINOBUTYRIC ACID
4-[(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)AMINO]-BUTANOIC ACID
4-[[(5Z,8Z,11Z,14Z)-1-OXO-5,8,11,14-EICOSATETRAENYL]AMINO]BUTANOIC ACID
Butanoic acid, 4-[[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]amino]-
[Molecular Formula]

C24H39NO3
[MDL Number]

MFCD05863981
[MOL File]

128201-89-8.mol
[Molecular Weight]

389.57
Chemical PropertiesBack Directory
[Fp ]

17°(63°F)
[storage temp. ]

Desiccate at -20°C
[solubility ]

DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 2 mg/ml
[form ]

Pale yellow viscous oil.
[color ]

Colorless to light yellow
[Sensitive ]

Air Sensitive
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
[Signal word ]

Danger
[Hazard statements ]

H225-H319
[Precautionary statements ]

P210-P240-P280a-P303+P361+P353-P305+P351+P338-P501a
[HazardClass ]

3
Hazard InformationBack Directory
[Uses]

N-Arachidonoyl-GABA is one member of a new class of lipoamino acids related to anandamide identified in bovine brain. N-Arachidonoyl-GABA displays analgesic activity[1].
[Definition]

ChEBI: N-arachidonoyl-gamma-aminobutyric acid is an N-acyl-gamma-aminobutyric acid resulting from the formal condensation of the amino group of gamma-aminobutyric acid with the carboxy group of arachidonic acid. It has a role as a mammalian metabolite. It is a fatty amide and a N-acyl-gamma-aminobutyric acid. It is functionally related to an arachidonic acid. It is a conjugate acid of a N-arachidonoyl-gamma-aminobutyrate.
[Biological Activity]

Arachidonyl amino acid; first isolated from bovine brain. Inhibits pain in vivo .
[storage]

Desiccate at -20°C
[References]

[1] Huang SM, et al. Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain. J Biol Chem. 2001 Nov 16;276(46):42639-44. DOI:10.1074/jbc.M107351200
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